| Orthodontic YouTube Channels | 200 | |
| Overwatch YouTube Channels | 145 | |
| Orlando YouTube Channels | 130 | |
| Outsourcing YouTube Channels | 118 | |
| Online Poker YouTube Channels | 115 | |
| Onlyfans YouTube Channels | 110 | |
| Overlanding YouTube Channels | 102 | |
| Outdoor Gear YouTube Channels | 102 | |
| Options Trading YouTube Channels | 96 | |
| Online Gambling YouTube Channels | 95 | |
| Outdoor Lighting YouTube Channels | 87 | |
| Omaha YouTube Channels | 87 | |
| Over 40 Beauty Youtubers YouTube Channels | 76 | |
| Outdoor YouTube Channels | 68 | |
| Occult YouTube Channels | 57 | |
| Outdoor Living YouTube Channels | 54 | |
| Ontario Lifestyle YouTube Channels | 42 | |
| Oil Painting YouTube Channels | 38 | |
| Office Productivity YouTube Channels | 37 | |
| Orthopedic YouTube Channels | 36 | |
| Organic Gardening YouTube Channels | 36 | |
| One Piece TCG YouTube Channels | 35 | |
| Osteopathy YouTube Channels | 35 | |
| Opera YouTube Channels | 35 | |
| Organizing YouTube Channels | 32 | |
| Optometry YouTube Channels | 32 | |
| Outdoor Kitchen YouTube Channels | 29 | |
| Off Road YouTube Channels | 28 | |
| Oregon YouTube Channels | 28 | |
| Oncology YouTube Channels | 27 | |
| Orchid YouTube Channels | 26 | |
| Osteoporosis YouTube Channels | 26 | |
| Omegle YouTube Channels | 26 | |
| Oklahoma YouTube Channels | 23 | |
| Orchestra YouTube Channels | 22 | |
| Oklahoma Sooners YouTube Channels | 22 | |
| Organic Food YouTube Channels | 22 | |
| Origami YouTube Channels | 21 | |
| Organic Beauty YouTube Channels | 21 | |
| Oregon Photography YouTube Channels | 21 | |
| Oman YouTube Channels | 20 | |
| Oracle YouTube Channels | 20 | |
| Ontario YouTube Channels | 20 | |
| Oregon Gardening YouTube Channels | 20 | |
| OCD YouTube Channels | 20 | |
| Ohio YouTube Channels | 20 | |
| Ohio State Buckeyes YouTube Channels | 20 | |
| Outdoor Gear Review YouTube Channels | 19 | |
| Oral Health YouTube Channels | 19 | |
| Orthodox YouTube Channels | 18 | |
| Oil and Gas YouTube Channels | 18 | |
| Ovarian Cancer YouTube Channels | 18 | |
| Oakville Real Estate YouTube Channels | 17 | |
| Ophthalmology YouTube Channels | 17 | |
| Oklahoma Law YouTube Channels | 17 | |
| Oklahoma Fishing YouTube Channels | 17 | |
| Ohio Photography YouTube Channels | 17 | |
| Ohio Real Estate YouTube Channels | 17 | |
| Ohio Gardening YouTube Channels | 16 | |
| Organic Farming YouTube Channels | 16 | |
| Oregon Fishing YouTube Channels | 16 | |
| Oboe YouTube Channels | 16 | |
| Oklahoma Photography YouTube Channels | 16 | |
| Ohio Fishing YouTube Channels | 16 | |
| Obgyn YouTube Channels | 15 | |
| Ohio Health YouTube Channels | 15 | |
| Oregon Real Estate YouTube Channels | 15 | |
| Oklahoma Gardening YouTube Channels | 15 | |
| Oklahoma Health YouTube Channels | 15 | |
| Oklahoma Real Estate YouTube Channels | 15 | |
| Omaha Lifestyle YouTube Channels | 15 | |
| Ohio News YouTube Channels | 15 | |
| Oregon Dental YouTube Channels | 15 | |
| Ohio Hunting YouTube Channels | 15 | |
| Oregon Health YouTube Channels | 15 | |
| Oklahoma Adoption YouTube Channels | 14 | |
| Oklahoma City Thunder YouTube Channels | 14 | |
| Occupational Therapy YouTube Channels | 13 | |
| Oregon State Beavers YouTube Channels | 13 | |
| Ohio Dental YouTube Channels | 12 | |
| Oregon Ducks YouTube Channels | 12 | |
| Ohio State Football YouTube Channels | 12 | |
| Oklahoma News YouTube Channels | 12 | |
| Oakland Athletics YouTube Channels | 10 | |
| Ocarina YouTube Channels | 10 | |
| Olympics YouTube Channels | 10 | |
| Ocean YouTube Channels | 10 | |
| Oregon News YouTube Channels | 10 | |
| Omaha Food YouTube Channels | 9 | |
| Orienteering YouTube Channels | 9 | |
